A Novel CMOS Base Handheld Device for Biological Luminescence Quantification [Biomedical Circuits and Systems]

Ude Lu, a member of Cozen O'Connor's Intellectual Property department, discusses this topic in Biomedical Circuits and Systems. In this report, a handheld luminescence system based on complementary metal oxide semiconductor (CMOS) was constructed. The system composed of two major parts - a CMOS photodiodes array integrated chip (IC) and a 8051 microprocessor based voltage monitor. The handheld device showed great performance to quantify the biological luminescence, either in Horse-radish-peroxidase (HRP)/luminol/H/sub 2/O/sub 2/ reaction system or in HRP/glucose oxidase (GOD)/glucose couple enzyme reaction system; and also showed great capacity for personalized healthcare device.

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