Cozen O’Connor: A Two-Stage Cascade Nonlinear Dynamical Model of Single Neurons for the Separation and Quantification of Pre- and Post-Synaptic Mechanisms of Synaptic Transmission [Engineering in Medicine and Biology Society]

A Two-Stage Cascade Nonlinear Dynamical Model of Single Neurons for the Separation and Quantification of Pre- and Post-Synaptic Mechanisms of Synaptic Transmission [Engineering in Medicine and Biology Society]

Ude Lu, a member of Cozen O'Connor's Intellectual Property Department, discusses this topic in Engineering in Medicine and Biology Society. eurons receive pre-synaptic spike trains and transform them into post-synaptic spike trains. This spike train to spike train temporal transformation underlies all cognitive functions performed by neurons, e.g., learning and memory. The transformation is a highly nonlinear dynamical process that involves both pre- and post-synaptic mechanisms. The ability to separate and quantify the nonlinear dynamics of pre- and post-synaptic mechanism is needed to gain insights into this transformation.

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Ude Lu, Ph.D.

Associate

ulu@cozen.com

(202) 471-3404


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